Nt5dc1^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nt5dc1^em1(IMPC)J
• Name: 5'-nucleotidase domain containing 1; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5649018
• Synonyms: Nt5dc1^em1J
• Gene: Nt5dc1 Location: Chr10:34179605-34294585 bp, - strand Genetic Position: Chr10, 18.85 cM
• Alliance: Nt5dc1^em1(IMPC)J page
• IMPC: Nt5dc1 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences ACCCCATTAGTGATTCTGCT, CAGTTCTTAGTCAAGGAGAA, and TTGTTCACCTGCATCCCCTG that targeted exon(s) ENSMUSE00001278401.2. This resulted in deletion(s) of 204 bp (location: Chr10:34287337-34287540; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nt5dc1 Mutation: 25 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)