Gt(ROSA)26Sor^{tm1(Stat5*)Ayr}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Stat5*)Ayr}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Alexander Y Rudensky
• MGI ID: MGI:5648718
• Synonyms: R26-STOP^fl-STAT5^CA/gfp
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Stat5*)Ayr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214587
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Constitutively active, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: A floxed stop cassette, constitutively active form of Stat5 and a EGFP reporter were inserted in the locus via homologous recombination. (J:214587)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:214587 Feng Y, et al., Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus. Cell. 2014 Aug 14;158(4):749-63
• All: 5 reference(s)