Tg(TG-KCNIP3*)15Cnbc
Transgene Detail
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Symbol: |
Tg(TG-KCNIP3*)15Cnbc |
Name: |
transgene insertion 15, Centro Nacional de Biotecnologia |
MGI ID: |
MGI:5646253 |
Synonyms: |
LeuBTA15 |
Transgene: |
Tg(TG-KCNIP3*)15Cnbc Location: unknown
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Alliance: |
Tg(TG-KCNIP3*)15Cnbc page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(TG-KCNIP3*)15Cnbc expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
KCNIP3 (30818) |
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Mutation details: The cDNA encoding human KCNIP3 (DREAM) with two aminoacid substitutions at EFhands 2, 3 and 4 (EFmDREAM) was inserted downstream of the bovine Thyroglobulin promoter to direct expression in the thyroid gland. The amino acid substitutions rendered the mutant insensitive to Ca2+.
(J:148712)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:148712 Rivas M, et al., The DREAM protein is associated with thyroid enlargement and nodular development. Mol Endocrinol. 2009 Jun;23(6):862-70 |
All: |
1 reference(s) |
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