Gt(ROSA)26Sor^tm1(SHH)Odk
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(SHH)Odk
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ophir D Klein
• MGI ID: MGI:5645956
• Synonyms: SHH-YFPcKI
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(SHH)Odk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213854
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^tm1(SHH)Odk expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SHH (6469)

  Shh	(MGI:98297)

• Mutation details: A floxed stop cassette followed by a cDNA encoding human SHH, an IRES, three nuclear localization signals and a Venus yellow fluorescent protein were inserted into the locus via homologous recombination. (J:213854)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:213854 Castillo D, et al., Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. Development. 2014 Aug;141(15):2993-3002
• All: 4 reference(s)