Tg(Tyr)2222Lmon
Transgene Detail

Summary

• Symbol: Tg(Tyr)2222Lmon
• Name: transgene insertion 2222, Lluis Montoliu
• MGI ID: MGI:5645915
• Synonyms: TYR5
• Transgene: Tg(Tyr)2222Lmon Location: unknown
• Alliance: Tg(Tyr)2222Lmon page

Transgene origin

• Strain of Origin: Hsd:NMRI

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: Transgenic mouse line carrying 1 copy of a reporter tyrosinase construct (TYR5) allowing pigmentation rescue of albino recipient strains and whose expression level is fully dependent on the site of integration and the number of copies of the mouse line. This line expresses low TYR5 levels, resulting in just pigmented eyes and very faint to non-existing coat color pigmentation. (J:185183)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:185183 Furlan-Magaril M, et al., An insulator embedded in the chicken alpha-globin locus regulates chromatin domain configuration and differential gene expression. Nucleic Acids Res. 2011 Jan;39(1):89-103
• All: 1 reference(s)