Tg(CMV-GAL4)1Wrk
Transgene Detail

Summary

• Symbol: Tg(CMV-GAL4)1Wrk
• Name: transgene insertion 1, Wolf Reik
• MGI ID: MGI:5645896
• Transgene: Tg(CMV-GAL4)1Wrk Location: unknown
• Alliance: Tg(CMV-GAL4)1Wrk page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/Ca)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CMV-GAL4)1Wrk expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  yeast	GAL4 (855828)

• Mutation details: A fusion protein of the DNA binding domain of yeast GAL4 to three copies of a nuclear localization signal (nls) and the human Myc epitope tag is expressed under the control of the CMV promoter. A high level of the protein is ubiquitously expressed. In combination with transgenic or knock-in strains carrying the target sequence for Gal4, UAS, the Gal4-myc fusion protein is targeted to the predetermined location with the UAS target site. (J:91713)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:91713 Murrell A, et al., Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat Genet. 2004 Aug;36(8):889-93
• All: 1 reference(s)