Tg(Gfap-tTA)7Igta
Transgene Detail

Summary

• Symbol: Tg(Gfap-tTA)7Igta
• Name: transgene insertion 7, Ignacio Torres-Aleman
• MGI ID: MGI:5645758
• Synonyms: GFAP7, pGFAPtTA
• Transgene: Tg(Gfap-tTA)7Igta Location: unknown
• Alliance: Tg(Gfap-tTA)7Igta page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: This construct expresses tet-transactivator (tTA) under the astrocyte-specific GFAP promoter (pGFAP). A 1.8 kb genomic fragment of the murine Gfap promoter was placed upstream of a gene coding for tTA. (J:145253)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:145253 Fernandez AM, et al., Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals. J Neurosci. 2007 Aug 15;27(33):8745-56
• All: 1 reference(s)