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Tg(Wap-Shh)119Mig
Transgene Detail
Summary
Symbol: Tg(Wap-Shh)119Mig
Name: transgene insertion 119, Marta I Gallego
MGI ID: MGI:5645728
Transgene: Tg(Wap-Shh)119Mig  Location: unknown  
Alliance: Tg(Wap-Shh)119Mig page
Transgene
origin
Strain of Origin:  (C57BL/6J x DBA/2J)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Wap-Shh)119Mig expresses 1 gene
 
Mutation detailsA mouse Shh cDNA was expressed under the control of a 1.6kb fragment of the mouse WAP (whey acidic protein) gene promoter sequence, the second intron of rabbit beta-globin gene and SV40 polyadenylation sequences. Northern blot analysis showed expression of transgenic Shh mRNA in lactating mammary glands from lactation day 1 (L1) primiparous transgenic mice. (J:222841)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:222841 Garcia-Zaragoza E, et al., Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland. Dev Biol. 2012 Dec 1;372(1):28-44
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory