Recql4^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Recql4^tm1.1Arte
• Name: RecQ protein-like 4; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5645319
• Synonyms: Recql4^fl, Recql4^tm2272Arte
• Gene: Recql4 Location: Chr15:76587753-76594748 bp, - strand Genetic Position: Chr15, 36.28 cM, cytoband D3
• Alliance: Recql4^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213779
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 9 and 10 were floxed and an F3 flanked puro cassette was inserted in intron 8 via homologous recombination. Flp mediated recombination removed the puro cassette. (J:213779)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Recql4 Mutation: 46 strains or lines available

References

• Original: J:213779 Smeets MF, et al., The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis. J Clin Invest. 2014 Aug 1;124(8):3551-65
• All: 4 reference(s)