Kcnd3^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kcnd3^em1(IMPC)J
• Name: potassium voltage-gated channel, Shal-related family, member 3; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5644712
• Synonyms: Kcnd3^em1J
• Gene: Kcnd3 Location: Chr3:105359646-105581318 bp, + strand Genetic Position: Chr3, 46.32 cM, cytoband F3
• Alliance: Kcnd3^em1(IMPC)J page
• IMPC: Kcnd3 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences AAGTGAGAGGACGTCCATGC, TGGTGCCTAAGACAATCGCA, and TGTTCGAGCAAGTGAGTGAT that targeted exon(s) ENSMUSE00001266672.2. This resulted in deletion(s) of 8 bp (location: Chr3:105565834-105565841; GRCm39), 327 bp (location: Chr3:105565861-105566187; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcnd3 Mutation: 62 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 6 reference(s)