Lrrk2^tm2Arte
Targeted Allele Detail

Summary

• Symbol: Lrrk2^tm2Arte
• Name: leucine-rich repeat kinase 2; targeted mutation 2, TaconicArtemis
• MGI ID: MGI:5644525
• Synonyms: Lrkk2^tm1149.2Arte
• Gene: Lrrk2 Location: Chr15:91557378-91700323 bp, + strand Genetic Position: Chr15, 46.07 cM, cytoband F1
• Alliance: Lrrk2^tm2Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211935
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The genomic region covering exon 41 through 47 was deleted. (J:211935)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrrk2 Mutation: 156 strains or lines available

References

• Original: J:211935 Dorval V, et al., Gene and MicroRNA transcriptome analysis of Parkinson's related LRRK2 mouse models. PLoS One. 2014;9(1):e85510
• All: 1 reference(s)