Slc39a10^tm1.2Tfk
Targeted Allele Detail

Summary

• Symbol: Slc39a10^tm1.2Tfk
• Name: solute carrier family 39 (zinc transporter), member 10; targeted mutation 1.2, Toshiyuki Fukada
• MGI ID: MGI:5642301
• Synonyms: Zip10^-
• Gene: Slc39a10 Location: Chr1:46846704-46932012 bp, - strand Genetic Position: Chr1, 24.07 cM
• Alliance: Slc39a10^tm1.2Tfk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213935
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP-neomycin-loxP cassette was inserted upstream of exon 6 followed by a third loxP site in intron 8. Recombination activities removed exons 6-8 and neomycin cassette. (J:213935)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc39a10 Mutation: 49 strains or lines available

References

• Original: J:213935 Miyai T, et al., Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11780-5
• All: 2 reference(s)