Rorb^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rorb^m2Btlr
• Name: RAR-related orphan receptor beta; mutation 2, Bruce Beutler
• MGI ID: MGI:5640755
• Synonyms: dee-no
• Gene: Rorb Location: Chr19:18907969-19088560 bp, - strand Genetic Position: Chr19, 13.28 cM
• Alliance: Rorb^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a T to C transition at base pair 18,955,053 (v38) on chromosome 19, or base pair 156,144 in the GenBank genomic region NC_000085. The mutation corresponds to residue 1,738 in the mRNA sequence NM_001043354 (variant 1) within exon 8 of 10 total exons, residue 1,204 in the mRNA sequence NM_146095 (variant 2) within exon 8 of 10 total exons, and residue 1,257 in the mRNA sequence NM_001289921 (variant 3) within exon 8 of 10 total exons. The mutation results in a leucine (L) to proline (P) substitution at position 367 (L367P) in isoform 1 and isoform 3 as well as L378P in isoform 2. (J:221488)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rorb Mutation: 38 strains or lines available

References

• Original: J:221488 Daniel C, et al., Mutagenetix entry for dee-no. MGI Direct Data Submission. 2015
• All: 1 reference(s)