Gt(ROSA)26Sor^{tm1(CAG-RFP,-CFP,-YFP)Mmw}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-RFP,-CFP,-YFP)Mmw}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Monte Winslow
• MGI ID: MGI:5638870
• Synonyms: R26^Motley, Rosa26Sor^Motley
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-RFP,-CFP,-YFP)Mmw} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217850
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector inserted into the locus a CAG promoter, loxN site, lox2272 site, loxP site, neomycin resistance cassette, loxN site, RFP reporter gene, lox2272 site, CFP reporter gene, loxP site and YFP reporter gene. (J:217850)

Tumor Data

List all tumor models in MMHCdb carrying Gt(ROSA)26Sor^{tm1(CAG-RFP,-CFP,-YFP)Mmw}

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:217850 Caswell DR, et al., Obligate progression precedes lung adenocarcinoma dissemination. Cancer Discov. 2014 Jul;4(7):781-9
• All: 3 reference(s)