Clic4^tm2Yus
Targeted Allele Detail

Summary

• Symbol: Clic4^tm2Yus
• Name: chloride intracellular channel 4; targeted mutation 2, Stuart H Yuspa
• MGI ID: MGI:5637800
• Synonyms: CLIC4-GFP
• Gene: Clic4 Location: Chr4:134941280-135000071 bp, - strand Genetic Position: Chr4, 67.19 cM, cytoband D3
• Alliance: Clic4^tm2Yus page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213573
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 2 was replaced with a GFP reporter gene (fused to amino acid 25) and floxed neomycin resistance cassette. Western blot analysis confirmed the absence of protein expression in the skin. (J:213573)

Expression

In Mice Carrying this Mutation:

117 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clic4 Mutation: 39 strains or lines available

References

• Original: J:213573 Padmakumar V, et al., Detection of differential fetal and adult expression of chloride intracellular channel 4 (CLIC4) protein by analysis of a green fluorescent protein knock-in mouse line. BMC Dev Biol. 2014;14:24
• All: 1 reference(s)