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Slc22a8tm1b(KOMP)Wtsi
Targeted Allele Detail
Summary
Symbol: Slc22a8tm1b(KOMP)Wtsi
Name: solute carrier family 22 (organic anion transporter), member 8; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5636960
Gene: Slc22a8  Location: Chr19:8568618-8589199 bp, + strand  Genetic Position: Chr19, 5.44 cM
Alliance: Slc22a8tm1b(KOMP)Wtsi page
IMPC: Slc22a8 gene page
Mutation
origin
Mutant Cell Line:  EPD0356_1_F12
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8A1.N3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsCre-mediated excision of the parental Slc22a8tm1a(KOMP)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc22a8 Mutation:  32 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory