Gt(ROSA)26Sor^{tm1(CAG-EGFP/Rpl10a)Brsp}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-EGFP/Rpl10a)Brsp}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Bruce M Spiegelman
• MGI ID: MGI:5636750
• Synonyms: EGFP-L10a, Gt(ROSA)26Sor^{tm1(CAG-EGFP*)Brsp}, TRAP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-EGFP/Rpl10a)Brsp} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214781
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced into the locus a CAG promoter, floxed stop cassette, WPRE sequence, and an EGFP reporter gene fusion with the 60S ribosomal subunit L10a (EGFP-L10a). (J:214781)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1058 strains or lines available

References

• Original: J:214781 Long JZ, et al., A smooth muscle-like origin for beige adipocytes. Cell Metab. 2014 May 6;19(5):810-20
• All: 3 reference(s)