Tg(Pbsn*-Mst1r)BSew
Transgene Detail

Summary

• Symbol: Tg(Pbsn*-Mst1r)BSew
• Name: transgene insertion B, Susan E Waltz
• MGI ID: MGI:5635793
• Synonyms: ARR2PB-Ron (Line B)
• Transgene: Tg(Pbsn*-Mst1r)BSew Location: unknown
• Alliance: Tg(Pbsn*-Mst1r)BSew page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pbsn*-Mst1r)BSew expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mst1r (MGI:99614)

• Mutation details: A transgenic construct containing a wild-type mouse minigene under the control of the Pb prostate-specific promoter consisting of two androgen response elements from the rat probasin gene promoter arranged sequentially. The full-length wild-type minigene consists of genomic DNA sequence of the first 3 exons and introns, and cDNA sequence encoding exons 4 though 19. Founder line B was subsequently established. (J:178109)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:178109 Gray JK, et al., Ron receptor overexpression in the murine prostate induces prostate intraepithelial neoplasia. Cancer Lett. 2012 Jan 1;314(1):92-101
• All: 2 reference(s)