Mirc37^tm1Gvdz
Targeted Allele Detail

Summary

• Symbol: Mirc37^tm1Gvdz
• Name: microRNA cluster 37, including Mir133b through Mir206; targeted mutation 1, Gregorio Valdez
• MGI ID: MGI:5635681
• Synonyms: 7H4^delta
• Gene: Mirc37 Location: unknown Genetic Position: Chr1, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215060
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: mixed

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion
• Mirc37^tm1Gvdz involves 2 genes/genome features (Mir206, Mir133b) View all
• Mutation details: Cre-mediated recombination between Mir133b^tm1.2Gfng and Mir206^tm1Eno removed the the 3.7 kb between the two deleted microRNAs that comprise the 7H4 transcript. (J:215060)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc37 Mutation: 0 strains or lines available

Notes

Strain of origin contains 129S/SvEv, 129S1/Sv, 129X1/SvJ and FVB/N.

References

• Original: J:215060 Valdez G, et al., The role of muscle microRNAs in repairing the neuromuscular junction. PLoS One. 2014;9(3):e93140
• All: 1 reference(s)