Adcyap1tm1.1(cre)Hze
Targeted Allele Detail
|
Symbol: |
Adcyap1tm1.1(cre)Hze |
Name: |
adenylate cyclase activating polypeptide 1; targeted mutation 1.1, Hongkui Zeng |
MGI ID: |
MGI:5635438 |
Synonyms: |
Adcyap1-2A-Cre, PACAP-2A-Cre |
Gene: |
Adcyap1 Location: Chr17:93506448-93513967 bp, + strand Genetic Position: Chr17, 60.67 cM
|
Alliance: |
Adcyap1tm1.1(cre)Hze page
|
|
|
Allele Type: |
|
Targeted (Recombinase) |
Mutation: |
|
Insertion
|
|
|
Adcyap1tm1.1(cre)Hze expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Adcyap1 (MGI:105094) |
|
|
|
|
Mutation details: The targeting vector contains from 5' to 3', a partial Adcyap1 sequence spanning intron 1 through part of exon 5 (with an FRT3 site in intron 4) up to but not including the endogenous stop codon, a viral 2A oligopeptide sequence (F2A; mediates ribosomal skipping), a Cre recombinase gene, a bovine growth hormone polyA sequence, an AttB site, a PGK-Neo, an FRT5 site, an mRNA splice acceptor sequence, the 3' portion of the hygromycin gene with SV40 polyA signal, and an AttP site. PhiC31-mediated recombination removed the AttB/AttP-flanked sequence (PGK-Neo-polyA::frt5::RNA splice acceptor::3'hygro-polyA) and replaced it with the recombined AttB/AttP site (AttL).
(J:220523)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Adcyap1
(mouse)
|
|
|
|
|
|
Original: |
J:220523 Harris JA, et al., Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation. Front Neural Circuits. 2014;8:76 |
All: |
17 reference(s) |
|