Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz
Transgene Detail

Summary

• Symbol: Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz
• Name: transgene insertion, Akira Kakizuka
• MGI ID: MGI:5634331
• Synonyms: V717F/P267S
• Transgene: Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz Location: unknown
• Alliance: Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: Two transgenes, one expressing a FLAG-tagged beta-c-terminal fragment of human APP with the Indiana mutation (V717F), and another with an HA-tagged full-length presenilin with the P267S mutation, both under the control of the neuron-specific enolase promoter were coinjected to generate the transgenic mice. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:212692)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:212692 Sasaoka N, et al., Long-term oral administration of hop flower extracts mitigates Alzheimer phenotypes in mice. PLoS One. 2014;9(1):e87185
• All: 1 reference(s)