Adamts20^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Adamts20^m4Btlr
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 20; mutation 4, Bruce Beutler
• MGI ID: MGI:5632160
• Synonyms: buckeye
• Gene: Adamts20 Location: Chr15:94166177-94329966 bp, - strand Genetic Position: Chr15, 48.2 cM
• Alliance: Adamts20^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a G to A transition at base pair 94,341,087 (Build 38) on Chromosome 15, or base pair 124,341 in the GenBank genomic region NC_000081. This site corresponds to nucleotide 2,510 in the mRNA sequence NM_177431 (isoform 1), within exon 16 of 39 total exons, and nucleotide 2,510 in the mRNA sequence NM_00164785 (isoform 2), within exon 16 of 28 total exons. The mutation results in a serine (S) to asparagine (N) substitution at amino acid position 750 (S750N) of both protein isoforms. (J:220067)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adamts20 Mutation: 93 strains or lines available

References

• Original: J:220067 SoRelle J, et al., Mutagenetix entry for buckeye (Last updated March 31, 2015). MGI Direct Data Submission. 2015
• All: 1 reference(s)