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Ddhd1tm1Katn
Targeted Allele Detail
Summary
Symbol: Ddhd1tm1Katn
Name: DDHD domain containing 1; targeted mutation 1, Katsuko Tani
MGI ID: MGI:5629572
Synonyms: Ddhd1tm1a(KOMP)Katn, PA-PLA1G
Gene: Ddhd1  Location: Chr14:45830628-45895600 bp, - strand  Genetic Position: Chr14, 23.14 cM
Alliance: Ddhd1tm1Katn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:212425
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsThe L1L2_gt2 cassette was inserted at position 45854541 of Chromosome 14 upstream of the critical exon 8 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. (J:212425)
Generation of the Ddhd1tm1Katn and Ddhd1tm1.1Katn alleles
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ddhd1 Mutation:  41 strains or lines available
References
Original:  J:212425 Baba T, et al., Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics. J Biol Chem. 2014 Apr 18;289(16):11497-511
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/24/2024
MGI 6.24
The Jackson Laboratory