Stxbp1^tm2.1Mver
Targeted Allele Detail

Summary

• Symbol: Stxbp1^tm2.1Mver
• Name: syntaxin binding protein 1; targeted mutation 2.1, Matthijs Verhage
• MGI ID: MGI:5629556
• Synonyms: Munc18-1-Venus
• Gene: Stxbp1 Location: Chr2:32677619-32737249 bp, - strand Genetic Position: Chr2, 22.09 cM
• Alliance: Stxbp1^tm2.1Mver page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217249
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Reporter) Mutation: Insertion Mutation details: A Venus reporter gene replaced the stop codon in exon 20. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of the reporter gene. (J:217249)

Generation of the Stxbp1^tm2.1Mver allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stxbp1 Mutation: 48 strains or lines available

References

• Original: J:217249 Cijsouw T, et al., Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner. J Cell Biol. 2014 Mar 3;204(5):759-75
• All: 3 reference(s)