Plxnd1^{tm2(EGFP/cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Plxnd1^{tm2(EGFP/cre/ERT2)Wtsi}
• Name: plexin D1; targeted mutation 2, Wellcome Trust Sanger Institute
• MGI ID: MGI:5629433
• Synonyms: Plxnd1^{tm2(cre/ERT2)Hmgu}
• Gene: Plxnd1 Location: Chr6:115931772-115971966 bp, - strand Genetic Position: Chr6, 53.72 cM
• Alliance: Plxnd1^{tm2(EGFP/cre/ERT2)Wtsi} page

Mutation origin

• Mutant Cell Line: CEPD0086_4_G06
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Plxnd1^{tm2(EGFP/cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Plxnd1 (MGI:2154244)

• Mutation details: According to the construct image presented by The International Mouse Knockout Consortium this allele has a single FRT site, an engrailed 2 splice acceptor site, an EGFP-cre/ERT2 cassette and a neomycin selection cassette that is driven by an automonous promoter all inserted in the intron between exons 9 and 10 and one loxP sequence inserted in the intron between exons 13 and 14. (J:155845)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Plxnd1 (mouse) Summary of all recombinase alleles driven by Plxnd1. Comparative matrix view of recombinase activities Alliance mouse Plxnd1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnd1 Mutation: 86 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)