Nrros^tm1Nju
Targeted Allele Detail

Summary

• Symbol: Nrros^tm1Nju
• Name: negative regulator of reactive oxygen species; targeted mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:5621190
• Gene: Nrros Location: Chr16:31961603-31984412 bp, - strand Genetic Position: Chr16, 22.4 cM
• Alliance: Nrros^tm1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212032
• Parent Cell Line: B6/BLU (ES Cell)
• Strain of Origin: C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A floxed neomycin resistance cassette replaced exon 4. (J:212032)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrros Mutation: 37 strains or lines available

References

• Original: J:212032 Su X, et al., Epigenetically modulated LRRC33 acts as a negative physiological regulator for multiple Toll-like receptors. J Leukoc Biol. 2014 Jul;96(1):17-26
• All: 1 reference(s)