Hhex^tm1.1Tes
Targeted Allele Detail

Summary

• Symbol: Hhex^tm1.1Tes
• Name: hematopoietically expressed homeobox; targeted mutation 1.1, Lino Tessarollo
• MGI ID: MGI:5620952
• Synonyms: Hhex^lox
• Gene: Hhex Location: Chr19:37423289-37429179 bp, + strand Genetic Position: Chr19, 32.28 cM, cytoband D1
• Alliance: Hhex^tm1.1Tes page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212335
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 2 through 4 were floxed. Flp-mediated recombination removed the neomycin resistance cassette inserted downstream of exon 4. (J:212335)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hhex Mutation: 15 strains or lines available

References

• Original: J:212335 Smith S, et al., LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways. PLoS One. 2014;9(1):e85883
• All: 2 reference(s)