Gata3^{tm1.1(cre)Gmlz}
Targeted Allele Detail

Summary

• Symbol: Gata3^{tm1.1(cre)Gmlz}
• Name: GATA binding protein 3; targeted mutation 1.1, Guillermo M Lanuza
• MGI ID: MGI:5619418
• Synonyms: Gata3^Cre
• Gene: Gata3 Location: Chr2:9861889-9894845 bp, - strand Genetic Position: Chr2, 6.69 cM
• Alliance: Gata3^{tm1.1(cre)Gmlz} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213157
• Parent Cell Line: 2A (ES Cell)
• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Gata3^{tm1.1(cre)Gmlz} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gata3 (MGI:95663)

• Mutation details: A cre recombinase gene and FRT flanked neomycin resistance cassette were inserted into exon 2 at the ATG. Flp-mediated recombination removed the selection cassette. (J:213157)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gata3 (mouse) Summary of all recombinase alleles driven by Gata3. Comparative matrix view of recombinase activities Alliance mouse Gata3 gene page

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata3 Mutation: 31 strains or lines available

References

• Original: J:213157 Zhang J, et al., V1 and v2b interneurons secure the alternating flexor-extensor motor activity mice require for limbed locomotion. Neuron. 2014 Apr 2;82(1):138-50
• All: 3 reference(s)