Ednra^m1Mhda
Chemically induced Allele Detail

Summary

• Symbol: Ednra^m1Mhda
• Name: endothelin receptor type A; mutation 1, Martin Hrabe de Angelis
• MGI ID: MGI:5618847
• Synonyms: abnormal ear #1, AEA001, Ednra^Y129F, Ednra^Y129FMhda, Mhdaaea1
• Gene: Ednra Location: Chr8:78389658-78451081 bp, - strand Genetic Position: Chr8, 36.63 cM, cytoband C2
• Alliance: Ednra^m1Mhda page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: The molecular lesion is a A-to-T substitution in codon 386 that alters the encoded residue from an alanine to a threonine (NM_010332.2:c.386A>T, NP_034462.1:p.Tyr129Phe). (J:237903)
• Inheritance: Dominant

Disease models

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	22 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ednra Mutation: 34 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 3 reference(s)