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Tg(Prox1-cre/ERT2)1Tmak
Transgene Detail
Summary
Symbol: Tg(Prox1-cre/ERT2)1Tmak
Name: transgene insertion 1, Taija Makinen
MGI ID: MGI:5617984
Synonyms: Prox1-CreERT2, Tg(Prox1-cre/ERT2)#aTmak
Transgene: Tg(Prox1-cre/ERT2)1Tmak  Location: unknown  
Alliance: Tg(Prox1-cre/ERT2)1Tmak page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Prox1-cre/ERT2)1Tmak expression driven by 1 gene
 
Mutation detailsThe BAC clone RP23-190F21 is used to generate a transgene in which a cre/ERT2 fusion was inserted at the Prox1 start codon. Two founders were generated and the one (line 1) with complete recombination in all Prox1-expressing tissues was used for further studies. (J:218590)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prox1 (mouse)
Summary of all recombinase alleles driven by Prox1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:218590 Bazigou E, et al., Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice. J Clin Invest. 2011 Aug;121(8):2984-92
All:  61 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory