Trip10^tm1Geha
Targeted Allele Detail

Summary

• Symbol: Trip10^tm1Geha
• Name: thyroid hormone receptor interactor 10; targeted mutation 1, Raif S Geha
• MGI ID: MGI:5614352
• Gene: Trip10 Location: Chr17:57556455-57570665 bp, + strand Genetic Position: Chr17, 29.74 cM
• Alliance: Trip10^tm1Geha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Exons 4 through 11 were replaced with an FRT flanked neo cassette. (J:101977, J:164363)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Trip10 Mutation: 30 strains or lines available

Notes

The version of this allele that does not contain the neomycin selection cassette, Trip10^tm1.1Geha, has been analyzed.

References

• Original: J:164363 Koduru S, et al., Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16252-6
• All: 2 reference(s)