Igsf9^tm2Kln
Targeted Allele Detail

Summary

• Symbol: Igsf9^tm2Kln
• Name: immunoglobulin superfamily, member 9; targeted mutation 2, Rudiger Klein
• MGI ID: MGI:5614204
• Synonyms: IgSF9^deltaC, IgSF9-deltaC
• Gene: Igsf9 Location: Chr1:172309355-172326445 bp, + strand Genetic Position: Chr1, 79.86 cM
• Alliance: Igsf9^tm2Kln page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209586
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• Mutation details: The cytoplasmic region encoded by exon 18 was replaced with a floxed neo cassette and a stop codon was created at the end of exon 17, 16 amino acids C terminal of the transmembrane domain. Western blot analysis confirmed the expression of a truncated protein. (J:209586)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igsf9 Mutation: 38 strains or lines available

References

• Original: J:209586 Mishra A, et al., Genetic evidence for the adhesion protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain. J Neurosci. 2014 Mar 19;34(12):4187-99
• All: 1 reference(s)