Tg(ZP2*)4Dean
Transgene Detail

Summary

• Symbol: Tg(ZP2*)4Dean
• Name: transgene insertion 4, Jurrien Dean
• MGI ID: MGI:5613982
• Synonyms: mo/huZP2
• Transgene: Tg(ZP2*)4Dean Location: unknown
• Alliance: Tg(ZP2*)4Dean page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(ZP2*)4Dean expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ZP2 (7783)

  Zp2	(MGI:99214)

• Mutation details: The full length sequence of the human ZP2 gene in BAC RP11-1023A8 is modified by replacing the corresponding mouse exons encoding amino acids 18-156 (bp 1 in exon 2 to bp 150 in exon 5) for the human amino acids 22-161 (bp 1 in exon 2 to bp 152 in exon 5) at the N-terminus of gene. (J:215794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:215794 Avella MA, et al., A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans. J Cell Biol. 2014 Jun 23;205(6):801-9
• All: 1 reference(s)