Tg(EEF1A1-SHC1)1Ravi
Transgene Detail
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Symbol: |
Tg(EEF1A1-SHC1)1Ravi |
Name: |
transgene insertion 1, Kodi S Ravichandran |
MGI ID: |
MGI:5613976 |
Synonyms: |
ShcWT |
Transgene: |
Tg(EEF1A1-SHC1)1Ravi Location: unknown
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Alliance: |
Tg(EEF1A1-SHC1)1Ravi page
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Transgene Type: |
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Transgenic (Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Tg(EEF1A1-SHC1)1Ravi expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
SHC1 (6464) |
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Mutation details: The transgenic construct contains a human eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) promoter/enhancer elements driving expression of a wildtype flag-tagged human src homology 2 domain-containing transforming protein C1 (SHC1) cDNA. The SHC1 sequence is fused to an internal ribosome entry site (IRES)-enhanced green fluorescent protein (EGFP) fusion protein, and is preceded by a loxP-flanked SV40 polyadenylation signal.
(J:118108)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:118108 Trampont P, et al., ShcA mediates the dominant pathway to extracellular signal-regulated kinase activation during early thymic development. Mol Cell Biol. 2006 Dec;26(23):9035-44 |
All: |
2 reference(s) |
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