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Targeted Allele Detail
Symbol: Tnfrsf19tm1.1(cre/ERT2)Cle
Name: tumor necrosis factor receptor superfamily, member 19; targeted mutation 1.1, Hans Clevers
MGI ID: MGI:5613002
Synonyms: Troy-eGFP-ires-CreERT2, Troy-kiki
Gene: Tnfrsf19  Location: Chr14:61201324-61283939 bp, - strand  Genetic Position: Chr14, 32.06 cM
Alliance: Tnfrsf19tm1.1(cre/ERT2)Cle page
Germline Transmission:  Earliest citation of germline transmission: J:214484
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
Tnfrsf19tm1.1(cre/ERT2)Cle expression driven by 1 gene
Mutation detailsAn EGFP, IRES, cre/ERT2 fusion, and floxed neomycin resistance cassette replaced the coding sequence in exon 2 and exon 3. Cre-mediated recombination removed the selection cassette. (J:214484)
 Tissue activity of this recombinase allele
Driver: Tnfrsf19 (mouse)
Summary of all recombinase alleles driven by Tnfrsf19.

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tnfrsf19 Mutation:  35 strains or lines available
Original:  J:214484 Stange DE, et al., Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium. Cell. 2013 Oct 10;155(2):357-68
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory