About   Help   FAQ
Tnfrsf19tm1.1(cre/ERT2)Cle
Targeted Allele Detail
Summary
Symbol: Tnfrsf19tm1.1(cre/ERT2)Cle
Name: tumor necrosis factor receptor superfamily, member 19; targeted mutation 1.1, Hans Clevers
MGI ID: MGI:5613002
Synonyms: Troy-eGFP-ires-CreERT2, Troy-kiki
Gene: Tnfrsf19  Location: Chr14:61201324-61283939 bp, - strand  Genetic Position: Chr14, 32.06 cM
Alliance: Tnfrsf19tm1.1(cre/ERT2)Cle page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:214484
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Tnfrsf19tm1.1(cre/ERT2)Cle expression driven by 1 gene
 
Mutation detailsAn EGFP, IRES, cre/ERT2 fusion, and floxed neomycin resistance cassette replaced the coding sequence in exon 2 and exon 3. Cre-mediated recombination removed the selection cassette. (J:214484)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tnfrsf19 (mouse)
Summary of all recombinase alleles driven by Tnfrsf19.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tnfrsf19 Mutation:  35 strains or lines available
References
Original:  J:214484 Stange DE, et al., Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium. Cell. 2013 Oct 10;155(2):357-68
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
07/05/2024
MGI 6.24
The Jackson Laboratory