Ephx2^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Ephx2^tm1.1Arte
• Name: epoxide hydrolase 2, cytoplasmic; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5609316
• Synonyms: sEH^fl
• Gene: Ephx2 Location: Chr14:66321823-66361949 bp, - strand Genetic Position: Chr14, 34.36 cM, cytoband D
• Alliance: Ephx2^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208344
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 4 and 5 were floxed and an FRT flanked selection cassette was inserted via homologous recombination. Flp mediated recombination removed the neo cassette. (J:208344)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ephx2 Mutation: 39 strains or lines available

References

• Original: J:208344 Hu J, et al., Muller glia cells regulate Notch signaling and retinal angiogenesis via the generation of 19,20-dihydroxydocosapentaenoic acid. J Exp Med. 2014 Feb 10;211(2):281-95
• All: 5 reference(s)