Klrb1c^tm1Fds
Targeted Allele Detail

Summary

• Symbol: Klrb1c^tm1Fds
• Name: killer cell lectin-like receptor subfamily B member 1C; targeted mutation 1, Fu-Dong Shi
• MGI ID: MGI:5606339
• Synonyms: NK1.1-tdTomato
• Gene: Klrb1c Location: Chr6:128755448-128765514 bp, - strand Genetic Position: Chr6, 63.09 cM
• Alliance: Klrb1c^tm1Fds page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206801
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a tdTomato reporter gene and an FRT flanked selection cassette. Reporter expression recapitulates endogenous gene expression. (J:206801)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klrb1c Mutation: 20 strains or lines available

References

• Original: J:206801 Gan Y, et al., Ischemic neurons recruit natural killer cells that accelerate brain infarction. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2704-9
• All: 2 reference(s)