Npy6r^tm1Hhzg
Targeted Allele Detail

Summary

• Symbol: Npy6r^tm1Hhzg
• Name: neuropeptide Y receptor Y6; targeted mutation 1, H Herzog
• MGI ID: MGI:5588329
• Gene: Npy6r Location: Chr18:44403194-44410767 bp, + strand Genetic Position: Chr18, 23.74 cM
• Alliance: Npy6r^tm1Hhzg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:210546
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An lacZ-IRES-neoR selection cassette was inserted into the coding frame. RT-PCR confirmed the absence of transcript expression in the hypothalamus, testis and inguinal white adipose tissue. (J:210546)

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npy6r Mutation: 27 strains or lines available

References

• Original: J:210546 Yulyaningsih E, et al., Pancreatic polypeptide controls energy homeostasis via Npy6r signaling in the suprachiasmatic nucleus in mice. Cell Metab. 2014 Jan 7;19(1):58-72
• All: 2 reference(s)