Ap1s1^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Ap1s1^{tm1.1(KOMP)Vlcg}
• Name: adaptor protein complex AP-1, sigma 1; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5585400
• Gene: Ap1s1 Location: Chr5:137063852-137074917 bp, - strand Genetic Position: Chr5, 76.13 cM, cytoband G1
• Alliance: Ap1s1^{tm1.1(KOMP)Vlcg} page
• IMPC: Ap1s1 gene page

Mutation origin

• Mutant Cell Line: 10776A-A12
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7551bp between positions 137511559-137519109 of Chromosome 5 (Genome Build37) and subsequent Cre-mediated excision deleted the neomycin selection cassette. (J:136110, J:188991)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ap1s1 Mutation: 15 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)