Tg(Cnp-EGFP*)1Qrlu
Transgene Detail

Summary

• Symbol: Tg(Cnp-EGFP*)1Qrlu
• Name: transgene insertion 1, Q Richard Lu
• MGI ID: MGI:5584296
• Synonyms: CNP-mEGFP
• Transgene: Tg(Cnp-EGFP*)1Qrlu Location: unknown
• Alliance: Tg(Cnp-EGFP*)1Qrlu page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The transgene was designed with a membrane-anchored green fluorescent protein (mEGFP), which carries a Ras membrane localization (CAAX) sequence in the carboxy terminus of EGFP, driven by a 3.9-kb 2',3'-cyclic nucleotide 3' phosphodiesterase (Cnp) promoter, followed by a human beta-globin polyadenylation site. Five lines were generated that displayed similar levels of expression. This is a representative record for all lines. (J:213410)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:213410 Deng Y, et al., Direct visualization of membrane architecture of myelinating cells in transgenic mice expressing membrane-anchored EGFP. Genesis. 2014 Apr;52(4):341-9
• All: 14 reference(s)