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Tg(tetO-Fgf10)1Jaw
Transgene Detail
Summary
Symbol: Tg(tetO-Fgf10)1Jaw
Name: transgene insertion 1, Jeffrey A Whitsett
MGI ID: MGI:5581842
Synonyms: Tet-Fgf10, (teto)7CMV-FGF-10
Transgene: Tg(tetO-Fgf10)1Jaw  Location: unknown  
Alliance: Tg(tetO-Fgf10)1Jaw page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(tetO-Fgf10)1Jaw expresses 1 gene
 
Mutation detailsThe transgenic insert is comprised of the mouse Fgf10 gene followed by the 3' UTR of the bovine growth hormone gene (polyA), under the control of (teto)7CMV, which contains seven direct repeats of the tetracycline operator sequence fused to a bidirectional cytomegalovirus (CMV) minimal promoter. Founder lines A and B (described in the original reference) were also generated. (J:68525)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:68525 Clark JC, et al., FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo. Am J Physiol Lung Cell Mol Physiol. 2001 Apr;280(4):L705-15
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory