Osr1^tm1Ryn
Targeted Allele Detail

Summary

• Symbol: Osr1^tm1Ryn
• Name: odd-skipped related transcription factor 1; targeted mutation 1, Ryuichi Nishinakamura
• MGI ID: MGI:5581722
• Synonyms: Osr1-GFP, Osr1^{tm1(GFP Neo+) #304Imeg}, Osr1^tm1Ryun
• Gene: Osr1 Location: Chr12:9624442-9631500 bp, + strand Genetic Position: Chr12, 4.05 cM
• Alliance: Osr1^tm1Ryn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206836
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: Insertion of EGFP into exon 2 results in an in-frame fusion at amino acid 12. A floxed neomycin resistance cassette was inserted downstream of EGFP. (J:206836)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Osr1 Mutation: 18 strains or lines available

References

• Original: J:206836 Taguchi A, et al., Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. Cell Stem Cell. 2014 Jan 2;14(1):53-67
• All: 2 reference(s)