Myo1g^tm1.1Mfk
Targeted Allele Detail

Summary

• Symbol: Myo1g^tm1.1Mfk
• Name: myosin IG; targeted mutation 1.1, Matthew F Krummel
• MGI ID: MGI:5581463
• Synonyms: Myo1g^FLOX
• Gene: Myo1g Location: Chr11:6456548-6470960 bp, - strand Genetic Position: Chr11, 4.3 cM, cytoband A1
• Alliance: Myo1g^tm1.1Mfk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212451
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT- and loxP-flanked neomycin resistance cassette was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exons 2 and 3 floxed. (J:212451)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo1g Mutation: 53 strains or lines available

References

• Original: J:212451 Gerard A, et al., Detection of Rare Antigen-Presenting Cells through T Cell-Intrinsic Meandering Motility, Mediated by Myo1g. Cell. 2014 Jul 31;158(3):492-505
• All: 2 reference(s)