Errfi1^tm2Gvw
Targeted Allele Detail

Summary

• Symbol: Errfi1^tm2Gvw
• Name: ERBB receptor feedback inhibitor 1; targeted mutation 2, George F Vande Woude
• MGI ID: MGI:5575858
• Synonyms: Mig-6^lacZ
• Gene: Errfi1 Location: Chr4:150938376-150953349 bp, + strand Genetic Position: Chr4, 81.5 cM, cytoband E1
• Alliance: Errfi1^tm2Gvw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206807
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Reporter) Mutation: Insertion Mutation details: A loxP-FRT-splice acceptor(SA)-LacZ-Neo-FRT-SA-exons 2 and 3-loxP cassette was inserted via homologous recombination. Reporter expression is seen in cells covering the surface of the knee joint cavity. (J:206807)

Generation of the Errfi1^tm2Gvw allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Errfi1 Mutation: 15 strains or lines available

References

• Original: J:206807 Staal B, et al., Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2590-5
• All: 1 reference(s)