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Cygbtm1Ppam
Targeted Allele Detail
Summary
Symbol: Cygbtm1Ppam
Name: cytoglobin; targeted mutation 1, Pradeep PA Mammen
MGI ID: MGI:5575764
Synonyms: Cygbflox
Gene: Cygb  Location: Chr11:116536421-116544887 bp, - strand  Genetic Position: Chr11, 81.45 cM, cytoband E2
Alliance: Cygbtm1Ppam page
Delayed regeneration of muscle in Cygbtm1Ppam/Cygbtm1Ppam Tg(Myog-cre)1Eno/0 mice after cardiotoxin injury

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:206378
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129 x C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    A loxP sequence was inserted in intron 1followed by a FRT-loxP-neo-FRT-loxP cassette in intron 3. (J:206378)
Generation of the Cygbtm1Ppam allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cygb Mutation:  17 strains or lines available
References
Original:  J:206378 Singh S, et al., Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E129-38
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory