Hprt1^em1Mvw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hprt1^em1Mvw
• Name: hypoxanthine phosphoribosyltransferase 1; endonuclease-mediated mutation 1, Michael Wiles
• MGI ID: MGI:5572799
• Synonyms: Hprt^null
• Gene: Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
• Alliance: Hprt1^em1Mvw page

Mutation origin

• Strain of Origin: NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/SzJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated by injecting Cas9 RNA and a specific single guide RNA (sgRNA) to create an 18 bp deletion, resulting in a frame shift and premature termination. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hprt1 Mutation: 1280 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)