Tas2r131tm2.1(cre)Uboe
Targeted Allele Detail
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Symbol: |
Tas2r131tm2.1(cre)Uboe |
Name: |
taste receptor, type 2, member 131; targeted mutation 2.1, Ulrich Boehm |
MGI ID: |
MGI:5569285 |
Synonyms: |
Tas2r131BLiC, Tas2r131F/MBLF/M-IRES-Cre |
Gene: |
Tas2r131 Location: Chr6:132933875-132934807 bp, - strand Genetic Position: Chr6, 64.03 cM
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Alliance: |
Tas2r131tm2.1(cre)Uboe page
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Allele Type: |
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Targeted (Epitope tag, Null/knockout, Recombinase) |
Mutations: |
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Insertion, Intragenic deletion
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Tas2r131tm2.1(cre)Uboe expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The Tas2r131 coding region was replaced with an expression cassette encoding the barley lectin (BL) sequence linked through an internal ribosome entry cassette to the cre recombinase sequence. Both flag and c-myc epitopes (for differential transsynaptic tracing) were inserted into the BL sequence at positions 79 and 597. An AFN (tACE-Flpe/NEOr) neomycin selection cassette, flanked by FRT sites was also inserted. The neomycin selection cassette was removed by crossing to Flpe-deleter. This allele is a Tas2r131 null and produces a bicistronic transcript BL and cre from the Tas2r131 promoter.
(J:200616, J:209852, J:309106)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Tas2r131
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tas2r131 Mutation: |
20 strains or lines available
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Original: |
J:200616 Foster SR, et al., Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart. PLoS One. 2013;8(5):e64579 |
All: |
5 reference(s) |
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