Setd1btm1.2Afst
Targeted Allele Detail
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Symbol: |
Setd1btm1.2Afst |
Name: |
SET domain containing 1B; targeted mutation 1.2, A Francis Stewart |
MGI ID: |
MGI:5568944 |
Synonyms: |
Setd1bFD |
Gene: |
Setd1b Location: Chr5:123280256-123306692 bp, + strand Genetic Position: Chr5, 62.8 cM
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Alliance: |
Setd1btm1.2Afst page
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: An FRT-flanked stop cassette containing a lacZ reporter, followed by loxP-flanked exon 5 and rox-flanked PGK-hygromycin cassette were inserted. Dre-recombination removed the PGK-hygromycin selection cassette. Flp mediated recombination removed the stop cassette leaving exon 5 floxed.
(J:208420)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Setd1b Mutation: |
49 strains or lines available
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Original: |
J:208420 Bledau AS, et al., The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation. Development. 2014 Mar;141(5):1022-35 |
All: |
4 reference(s) |
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