Sv2c^tm1Dda
Targeted Allele Detail

Summary

• Symbol: Sv2c^tm1Dda
• Name: synaptic vesicle glycoprotein 2c; targeted mutation 1, David Dardou
• MGI ID: MGI:5568123
• Gene: Sv2c Location: Chr13:96091102-96269085 bp, - strand Genetic Position: Chr13, 50.47 cM, cytoband D1
• Alliance: Sv2c^tm1Dda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209562
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exon 3. Immunohistochemistry confirmed the absence of protein expression in the anterior and posterior regions of the brain. (J:209562)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sv2c Mutation: 51 strains or lines available

References

• Original: J:209562 Dardou D, et al., Distribution of SV2C mRNA and protein expression in the mouse brain with a particular emphasis on the basal ganglia system. Brain Res. 2011 Jan 7;1367:130-45
• All: 2 reference(s)