Pgr^tm2.1Mlia
Targeted Allele Detail

Summary

• Symbol: Pgr^tm2.1Mlia
• Name: progesterone receptor; targeted mutation 2.1, M Luisa Iruela-Arispe
• MGI ID: MGI:5566874
• Synonyms: PR^LacZ, PRLacZ
• Gene: Pgr Location: Chr9:8899834-8968612 bp, + strand Genetic Position: Chr9, 2.46 cM
• Alliance: Pgr^tm2.1Mlia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205553
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A lacZ gene and floxed neo cassette were inserted into exon 1 directly downstream of the PR-B initiation site. Cre mediated recombination removed the neo cassette. (J:205553)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgr Mutation: 76 strains or lines available

References

• Original: J:205553 Goddard LM, et al., Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation. Cell. 2014 Jan 30;156(3):549-62
• All: 1 reference(s)